基本信息 |
|
| 产品名称： | 3'-叠氮-3'-脱氧胸苷 |
| CAS： | 30516-87-1 ;146426-54-2 ;162537-11-3 |
| 中文同义词： | 齐多夫定 ; 叠氮胸苷 ; 3'-叠氮-3'-脱氧胸苷 ; 3′-叠氮-3′-脱氧胸苷 ; 1-(3-叠氮基-2,3-二脱氧-β-D-呋喃核糖基)胸腺嘧啶 |
| 英文同义词： | 3'-AZIDO-2',3'-DIDEOXYTHYMIDINE ; RETROVIS ; 1-((2R,4S,5S)-4-AZIDO-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE ; AZIDOTHYMIDINE ; 3′-AZIDO-3′-DEOXYTHYMIDINE ; AZT ; 1-((3S,4R)-4-(METHYLTHIO)TETRAHYDROFURAN-3-YL)PIPERAZINE ; TIMAZID ; ZDV ; 1-[(2R,4S,5S)-4-AZIDO-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5-METHYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE ; 3'-AZIDO-3'-DEOXYTHYMIDINE ; 1-(3-AZIDO-2,3-DIDEOXY-BETA-D-RIBOFURANOSYL)-5-METHYLPYRIMIDINE-2,4-(1H,3H)-DIONE ; 3-AZIDO-1,2,3-TRIDEOXY-1-(3,4-DIHYDRO-5-METHYL-2,4-DIOXO-1(2H)-PYRIMIDINYL)-D-ERYTHRO-PENTOFURANURONIC ACID ; RETROVIR ; ZIDOVUDINE ; 1-((2R,4S,5S)-4-AZIDO-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-5-METHYL-1H-PYRIMIDINE-2,4-DIONE |
| MDL号： | MFCD00006536 |
| 氢键受体数量： | 9 |
| 氢键供体数量： | 2 |
| Smile： | Cc1cn(c(=O)[nH]c1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-] |
| InChi： | InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1 |
| InChiKey： | InChIKey=HBOMLICNUCNMMY-XLPZGREQSA-N |
性质 |
|
| 熔点： | 113-115 DEG C(LIT) |
| 注解： | ASSAY METHOD: HPLC BIOCHEM/PHYSIOL ACTIONS: REVERSE TRANSCRIPTASE INHIBITOR ACTIVE AGAINST HIV-1 VIRUS OTHER NOTES: A POTENT, SELECTIVE INHIBITOR OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION IN MT-4 AND ATH8 CELLS RTECS: XP2072000 SOLUBILITY: H2O: SOLUBLE 50 MG/ML, CLEAR, COLORLESS TO SLIGHTLY YELLOW STORAGE TEMPERATURE: -20 DEG C TOTAL IMPURITIES: UNSPSC: 12352200 WGK: 3 |
安全信息 |
|
| 符号： |
GHS08
|
| 信号词： | Warning |
| 危险声明： | H351 |
| 警示性声明： | P281 |
| 危害码： | Xn |
| 风险声明： | R:40 |
| 安全声明： | S:36/37/39-45 |
| WGK德国： | 3 |
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