basic_info |
|
| Product_Name： | 链脲霉素 |
| CAS： | 18883-66-4 ;66395-18-4 ;72521-89-2 |
| 中文同义词： | 链脲霉素 ; 链脲菌素(STZ) ; 链脲佐菌素 |
| EnglishSynonyms： | 2-DESOXY-2-(3-METHYL-3-NITROSOUREIDO)-D-GLUCOPYRANOSE ; N-(METHYLNITROSOCARBAMOYL)-ALPHA-D-GLUCOSAMINE ; STREPTOZOTOCIN ; 2-DEOXY-2-(3-METHYL-3-NITROSOUREIDO)-D-GLUCOPYRANOSE ; STREPTOZOCIN ; STZ ; 2-DEOXY-2[([METHYL-NITROSOAMINO]-CARBONYL)-AMINO]-D-GLUCOPYRANOSE ; ZANOSAR |
| pro_mdlNumber： | MFCD00006607 |
| pro_acceptors： | 10 |
| pro_donors： | 5 |
| pro_smile： | CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO)O)O)N=O |
| InChi： | InChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1 |
| InChiKey： | InChIKey=ZSJLQEPLLKMAKR-GKHCUFPYSA-N |
property |
|
| MeltingPoint： | 121 DEG C (DEC)(LIT)/115℃ |
| Comments： | ASSAY METHOD: HPLC BIOCHEM/PHYSIOL ACTIONS: AN N-NITROSO-CONTAINING COMPOUND THAT ACTS AS A NITRIC OXIDE DONOR IN PANCREATIC ISLETS BIOCHEM/PHYSIOL ACTIONS: INDUCES DEATH OF INSULIN-SECRETING CELLS, PRODUCING AN ANIMAL MODEL OF DIABETES. POTENT DNA METHYLATING AGENT THAT INDUCES CHROMOSOMAL BREAKAGE. CYTOTOXIC TO NEUROENDOCRINE TUMOR CELL LINES THAT EXPRESS THE GLUT2 GLUCOSE TRANSPORTER RTECS: LZ5775000 STORAGE TEMPERATURE: -20 DEG C UNSPSC: 12352200 WGK: 3 |
secure_info |
|
| secure_symbol： |
GHS08
|
| secure_signal_word： | Danger |
| secure_risk_stmt： | H350 |
| secure_cautionary_stmt： | P201-P308 + P313 |
| secure_damage_code： | T |
| secure_risk_disclosure_stmt： | R:45 |
| secure_security_stmt： | S:53-45 |
| secure_wgk_germany： | 3 |
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