basic_info |
|
| Product_Name： | 芹菜素 |
| CAS： | 520-36-5 |
| 中文同义词： | 4',5,7-三羟基黄酮 ; 芹菜素 ; 5,7,4'-三羟基黄酮 ; 芹黄素 |
| EnglishSynonyms： | 4',5,7-TRIHYDROXYFLAVONE ; CI NATURAL YELLOW 1 ; APIGENOL ; APIGENINE ; 4,5,7-TRIHYDROXYFLAVONE ; 5,7,4'-TRIHYDROXYFLAVONE ; 5,7-DIHYDROXY-2-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE ; 7,4,5'-TRIHYDROXYFLAVONE ; 2-(P-HYDROXYPHENYL)-5,7-DIHYDROXYCHROMONE ; 5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE ; MATRICARIA OIL ; APIGENIN ; VERSULIN ; CHAMOMILE ; 5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE |
| pro_mdlNumber： | MFCD00006831 |
| pro_acceptors： | 5 |
| pro_donors： | 3 |
| pro_smile： | c1cc(ccc1c2cc(=O)c3c(cc(cc3o2)O)O)O |
| InChi： | InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H |
| InChiKey： | InChIKey=KZNIFHPLKGYRTM-UHFFFAOYSA-N |
property |
|
| MeltingPoint： | >300 DEG C(LIT)/345-350℃/345-350℃ |
| Comments： | ASSAY METHOD: =>75% (HPLC) BIOCHEM/PHYSIOL ACTIONS: A PLANT FLAVONOID THAT HAS BEEN FOUND TO INHIBIT CELL PROLIFERATION BY ARRESTING THE CELL CYCLE AT THE G2/M PHASE. INHIBITION OF GROWTH THROUGH CELL CYCLE ARREST AND INDUCTION OF APOPTOSIS APPEAR TO BE RELATED TO INDUCTION OF P53.INHIBITS PMA-MEDIATED TUMOR PROMOTION BY INHIBITING PROTEIN KINASE C1 AND THE RESULTING SUPPRESSION OF ONCOGENE EXPRESSION. IT HAS ALSO BEEN REPORTED TO INHIBIT TOPOISOMERASE I-CATALYZED DNA RE-LIGATION AND ENHANCE GAP JUNCTIONAL INTERCELLULAR COMMUNICATION RTECS: LK9276000 STORAGE TEMPERATURE: -20 DEG C TOTAL IMPURITIES: WGK: 3 |
| Information： | BIOLOGICAL SOURCE: FROM PARSLEY |
secure_info |
|
| secure_symbol： |
GHS07
|
| secure_signal_word： | Warning |
| secure_risk_stmt： | H315-H319-H335 |
| secure_cautionary_stmt： | P261-P305 + P351 + P338 |
| secure_damage_code： | Xi |
| secure_risk_disclosure_stmt： | R:36/37/38 |
| secure_security_stmt： | S:26-36 |
| secure_wgk_germany： | 3 |
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