basic_info |
|
| Product_Name： | 曲安西龙 |
| CAS： | 124-94-7 |
| 中文同义词： | 曲安西龙 |
| EnglishSynonyms： | TRI-NASAL ; TRIADERM ; 9ALPHA-FLUORO-11BETA,16ALPHA,17,21-TETRAHYDROXY-1,4-PREGNADIENE-3,20-DIONE ; FLUOXYPREDNISOLONE ; 1,4-PREGNADIEN-9ALPHA-FLUORO-11BETA,16ALPHA,17,21-TETROL-3,20-DIONE ; 9ALPHA-FLUORO-11BETA,16ALPHA,17,21-TETRAHYDROXYPREGNA-1,4-DIENE-3,20-DIONE ; (8S,9R,10S,11S,13S,14S,16R,17S)-9-FLUORO-11,16,17-TRIHYDROXY-17-(2-HYDROXY-ACETYL)-10,13-DIMETHYL-6,7,8,9,10,11,12,13,14,15,16,17-DODECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE ; KENACORT ; TRIAMCINOLONE |
| pro_mdlNumber： | MFCD00010477 |
| pro_acceptors： | 6 |
| pro_donors： | 4 |
| pro_smile： | C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@H]([C@@]2(C(=O)CO)O)O)CCC4=CC(=O)C=C[C@@]43C)F)O |
| InChi： | InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1 |
| InChiKey： | InChIKey=GFNANZIMVAIWHM-OBYCQNJPSA-N |
property |
|
| MeltingPoint： | 262-263 DEG C(LIT) |
| Comments： | BIOCHEM/PHYSIOL ACTIONS: IMPAIRS TUMOR NECROSIS FACTOR (TNF)-ALPHA-INDUCED DEGRADATION OF KAPPAB-ALPHA BIOCHEM/PHYSIOL ACTIONS: INDUCES GENE EXPRESSION AND APOPTOSIS BIOCHEM/PHYSIOL ACTIONS: INHIBITS PROSTAGLANDIN SYNTHESIS BIOCHEM/PHYSIOL ACTIONS: POTENTIATES THE DIFFERENTIATION-INDUCING EFFECTS OF BONE MORPHOGENETIC PROTEINS (BMP-2, -4, -6) BIOCHEM/PHYSIOL ACTIONS: TRIAMCINOLONE IS A SYNTHETIC GLUCOCORTICOID AGONIST OPTICAL ACTIVITY: [ALPHA]25/D +69 DEG, C = 2 IN DMF RTECS: TU3850000 UNSPSC: 12352100 WGK: 3 |
secure_info |
|
| secure_symbol： |
GHS08
|
| secure_signal_word： | Warning |
| secure_risk_stmt： | H351 |
| secure_cautionary_stmt： | P281 |
| secure_damage_code： | Xn |
| secure_risk_disclosure_stmt： | R:40 |
| secure_security_stmt： | S:22-36 |
| secure_wgk_germany： | 3 |
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