基本信息 |
|
| 产品名称： | 盐酸二甲双胍 |
| CAS： | 1115-70-4 |
| 中文同义词： | 盐酸二甲双胍 |
| 英文同义词： | DIABETOSAN, HYDROCHLORIDE ; RIOMET ; DIABEX, HYDROCHLORIDE ; GLUCOFORM, HYDROCHLORIDE ; ORABET, HYDROCHLORIDE ; METFORMIN (HYDROCHLORIDE) ; GLUCOPHAGE ; GLUCOMET, HYDROCHLORIDE ; METFORMIN HYDROCHLORIDE, 99% PHARMACEUTICAL GRADE ; SIAMFORMET, HYDROCHLORIDE ; METFORMIN ; GLUCOPHAGE, HYDROCHLORIDE ; METIGUANIDE, HYDROCHLORIDE ; N,N-DIMETHYLIMIDODICARBONIMIDIC DIAMINE HYDROCHLORIDE ; METFORMIN HYDROCHLORIDE ; GLUCOMINE, HYDROCHLORIDE ; GLUCOMIN, HYDROCHLORIDE ; 1-CARBAMIMIDAMIDO-N,N-DIMETHYLMETHANIMIDAMIDE HYDROCHLORIDE ; DIABETOSAN ; DIABEX ; METFORMIN HCL ; N,N-DIMETHYLIMIDODICARBONIMIDIC DIAMIDE HYDROCHLORIDE ; WALAPHAGE, HYDROCHLORIDE ; 1,1-DIMETHYLBIGUANIDE HYDROCHLORIDE |
| MDL号： | MFCD00012582 |
| 氢键受体数量： | 5 |
| 氢键供体数量： | 4 |
| Smile： | CN(C)C(=N)NC(=N)N.Cl |
| InChi： | InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H |
| InChiKey： | InChIKey=OETHQSJEHLVLGH-UHFFFAOYSA-N |
性质 |
|
| 熔点： | 223-226 DEG C(LIT) |
| 注解： | BIOCHEM/PHYSIOL ACTIONS: METFORMIN IS AN ANTIDIABETIC AGENT THAT REDUCES BLOOD GLUCOSE LEVELS AND IMPROVES INSULIN SENSITIVITY. ITS METABOLIC EFFECTS, INCLUDING THE INHIBITION OF HEPATIC GLUCONEOGENESIS, ARE MEDIATED AT LEAST IN PART BY ACTIVATION OF THE LKB1-AMPK (AMP-ACTIVATED PROTEIN KINASE) PATHWAY. ACTIVATION OF THIS PATHWAY ALSO APPEARS TO BE INVOLVED IN THE ANTIPROLIFERATIVE AND PROAPOPTOTIC ACTIONS OF METFORMIN IN CANCER CELL LINES FREQUENTLY ASKED QUESTIONS: LIVE CHAT AND FREQUENTLY ASKED QUESTIONS ARE AVAILABLE FOR THIS PRODUCT RTECS: DU1800000 UNSPSC: 12352100 WGK: 3 |
安全信息 |
|
| 符号： |
GHS07
|
| 信号词： | Warning |
| 危险声明： | H302-H315-H319 |
| 警示性声明： | P305 + P351 + P338 |
| 危害码： | Xn |
| 风险声明： | R:22-36/38 |
| 安全声明： | S:26-36 |
| WGK德国： | 3 |
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