磷雷素钠 ,26016-99-9 _化学云数据库

磷雷素钠

基本信息
产品名称：	磷雷素钠
CAS：	26016-99-9 ;4719-75-9
中文同义词：	磷雷素钠 ; 磷霉素钠
英文同义词：	PHOSPHOMYCIN DISODIUM SALT ; DISODIUM PHOSPHONOMYCIN ; (2R-CIS)-(3-METHYLOXIRANYL) PHOSPHONIC ACID DISODIUM SALT ; (-)-(1R,2S)-(1,2-EPOXYPROPYL)PHOSPHONIC ACID DISODIUM SALT ; FOSFOMYCIN DISODIUM SALT ; DISODIUM FOSFOMYCIN ; TETRASODIUM FOSFESTROL ; PHOSPHONOMYCIN DISODIUM SALT ; DISODIUM (1R,2S)-(1,2-EPOXYPROPYL)PHOSPHONATE ; (1R,2S)(-)-(1,2-EPOXYPROPYL) PHOSPHONIC ACID DISODIUM SALT ; FOSFOMYCIN SODIUM ; FOSFOMYCIN ; FOM-NA ; FOSFOMYCIN DISODIUM ; PHOSPHONOMYCIN
MDL号：	MFCD00056853
氢键受体数量：	4
氢键供体数量：	0
Smile：	C[C@@H]1[C@@H](O1)P(=O)([O-])[O-].[Na+].[Na+]
InChi：	InChI=1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m1../s1
InChiKey：	InChIKey=QZIQJIKUVJMTDG-OTUWWBTESA-L
性质
注解：	BIOCHEM/PHYSIOL ACTIONS: ANTIBIOTIC THAT CONCENTRATES IN KIDNEY AND BLADDER BIOCHEM/PHYSIOL ACTIONS: REDUCES NEPHROTOXICITY AND OTOTOXICITY OF PLATINUM-CONTAINING ANTI-TUMOR AGENTS. FOSFOMYCIN IS A PHOSPHOENOLPYRUVATE ANALOG THAT IRREVERSIBLY INHIBITS UDP-GLCNAC ENOLPYRUVYL TRANFERASE (MURA), AN ENZYME INVOLVED IN BACTERIAL CELL WALL BIOSYNTHESIS. AS A RESULT, THE PRODUCTION OF N-ACETYLMURAMIC ACID, AN ESSENTIAL ELEMENT OF THE PEPTIDOGLYCAN CELL WALL, IS INHIBITED LEGAL INFORMATION: VETRANAL IS A TRADEMARK OF SIGMA-ALDRICH CO LLC WGK: 3
规格：	VETRANAL(TM)
安全信息

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