基本信息 |
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| 产品名称： | 柠檬酸他莫西芬 |
| CAS： | 10540-29-1 ;54965-24-1 |
| 中文同义词： | 柠檬酸他莫西芬 ; 他莫昔芬柠檬酸盐 |
| 英文同义词： | (2-(4-[(1Z)-1,2-DIPHENYLBUT-1-EN-1-YL]PHENOXY)ETHYL)DIMETHYLAMINE, 2-HYDROXYPROPANE-1,2,3-TRICARBOXYLIC ACID ; TERIMON ; ISTUBAL ; (Z)-1-(4-DIMETHYLAMINOETHOXYPHENYL)-1,2-DIPHENYL-1-BUTENE CITRATE ; (Z)-2-(4-(1,2-DIPHENYL-1-BUTENYL)PHENOXYL)-N,N-DIMETHYL-ETHANAMINE-CITRATE ; TAMOXIFEN ; (Z)-1-(P-DIMETHYLAMINOETHOXYPHENYL)-1,2-DIPHENYL-1-BUTENE CITRATE SALT ; NOLTAM ; ZYNOPLEX ; TAMOXIFENCITRATE ; TAMOXIFEN CITRATE ; VALODEX ; KESSAR ; ETHANAMINE, 2-[4-[(1Z)-1,2-DIPHENYL-1-BUTENYL]PHENOXY]-N,N-DIMETHYL-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (1:1) SALT ; (Z)-2-[4-(1,2-DIPHENYL-1-BUTENYL)PHENOXY]-N,N-DIMETHYLETHANAMINE CITRATE ; (Z)-1-(P-DIMETHYLAMINOETHOXYPHENYL)-1,2-DIPHENYL-1-BUTENE CITRATE ; TAMOXIFEN CITRATE SALT ; (2-[4-(1,2-DIPHENYL-1-BUTEN-1-YL)PHENOXY]ETHYL)DIMETHYLAMINE 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE SALT ; TAMOXIFEN DRUG STANDARD SOLUTION ; TAMOXIFEN (CITRATE) ; Z-TAMOXIFEN CITRATE ; TAMOXASTA ; NOLVADEX ; CIS-1-(4-DIMETHYLAMINOETHOXYPHENYL)-1,2-DIPHENYL-1-BUTENE CITRATE ; TAMOFEN |
| MDL号： | MFCD00058321 |
| 氢键受体数量： | 2 |
| 氢键供体数量： | 0 |
| Smile： | CC/C(=C(\c1ccccc1)/c2ccc(cc2)OCCN(C)C)/c3ccccc3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
| InChi： | InChI=1S/C26H29NO.C6H8O7/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,4,19-20H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-; |
| InChiKey： | InChIKey=FQZYTYWMLGAPFJ-OQKDUQJOSA-N |
性质 |
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| 熔点： | 140-144 °C |
| 注解： | BIOCHEM/PHYSIOL ACTIONS: PROTEIN KINASE C INHIBITOR. INDUCES APOPTOSIS IN HUMAN MALIGNANT GLIOMA CELL LINES. TAMOXIFEN AND ITS METABOLITE 4-HYDROXYTAMOXIFEN ARE SELECTIVE ESTROGEN RESPONSE MODIFIERS (SERMS) THAT ACT AS ESTROGEN ANTAGONISTS IN MAMMARY GLAND. BLOCKS ESTRADIOL-STIMULATED VEGF PRODUCTION IN BREAST TUMOR CELLS FOR PERFORMANCE TEST GENERAL DESCRIPTION: THIS PRODUCT IS PROVIDED AS DELIVERED AND SPECIFIED BY THE ISSUING PHARMACOPOEIA. ALL INFORMATION PROVIDED IN SUPPORT OF THIS PRODUCT, INCLUDING MSDS AND ANY PRODUCT INFORMATION LEAFLETS HAVE BEEN DEVELOPED AND ISSUED UNDER THE AUTHORITY OF THE ISSUING PHARMACOPOEIA. FOR FURTHER INFORMATION AND SUPPORT PLEASE GO TO THE WEBSITE OF THE ISSUING PHARMACOPOEIA OTHER NOTES: SALES RESTRICTIONS MAY APPLY |
安全信息 |
|
| 符号： |
GHS07
GHS08
|
| 信号词： | Danger |
| 危险声明： | H302-H350-H360 |
| 警示性声明： | P201-P308 + P313 |
| 危害码： | T |
| 风险声明： | R:45-60-61-22-64 |
| 安全声明： | S:36/37/39-45 |
| WGK德国： | 3 |
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