basic_info |
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| Product_Name： | 洛伐他汀 |
| CAS： | 74133-25-8 ;75330-75-5 |
| 中文同义词： | 洛伐司他汀 ; (S)-2-甲基丁酸-(1S,3S,7S,8S,8aR) 1,2,3,7,8,8a-六氢-3,7-二甲基-8-{2-[(2R,4R)-4-羟基-6-氧代-2-四氢吡喃基]-乙基}-1-酯 ; 洛伐他汀 ; 洛伐他丁 |
| EnglishSynonyms： | 2-METHYL-1,2,3,7,8,8A-HEXAHYDRO-3,7-DIMETHYL-8-[2-(TETRAHYDRO-4-HYDROXY-6-OXO-2H-PYRAN-2-YL)ETHYL]-1-NAPHTHALENYL ESTER BUTANOIC ACID ; LOVALIP ; MEVACOR ; BUTANOIC ACID, 2-METHYL-, (1S,3R,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-3,7-DIMETHYL-8-[2-[(2R,4R)-TETRAHYDRO-4-HYDROXY-6-OXO-2H-PYRAN-2-YL]ETHYL]-1-NAPHTHALENYL ESTER, (2S)- ; (S)-2-METHYL-BUTYRIC ACID (1S,3R,7S,8S,8AR)-8-[2-((2R,4R)-4-HYDROXY-6-OXO-TETRAHYDRO-PYRAN-2-YL)-ETHYL]-3,7-DIMETHYL-1,2,3,7,8,8A-HEXAHYDRO-NAPHTHALEN-1-YL ESTER ; 8-[2-(4-HYDROXY-6-OXOTETRAHYDRO-2H-PYRAN-2-YL)ETHYL]-3,7-DIMETHYL-1,2,3,7,8,8A-HEXAHYDRO-1-NAPHTHALENYL 2-METHYLBUTANOATE ; MK-803 ; LOVASTATIN ; (1S,3R,7S,8S,8AR)-8-(2-[(2R,4R)-4-HYDROXY-6-OXOOXAN-2-YL]ETHYL)-3,7-DIMETHYL-1,2,3,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL (2S)-2-METHYLBUTANOATE ; 2-METHYL-1S,2,3R,7S,8S,8AR-HEXAHYDRO-3,7-DIMETHYL-8-[2-[(2R,4R)-TETRAHYDRO-4-HYDROXY-6-OXO-2H-PYRAN-2-YL]ETHYL]-1-NAPHTHALENYL ESTER, BUTANOIC ACID ; (S)-((1S,3R,7S,8S,8AR)-8-(2-((2R,4R)-4-HYDROXY-6-OXO-TETRAHYDRO-2H-PYRAN-2-YL)ETHYL)-3,7-DIMETHYL-1,2,3,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL) 2-METHYLBUTANOATE ; (1S,3R,7S,8S,8AR)-8-(2-((2R,4R)-4-HYDROXY-6-OXOTETRAHYDRO-2H-PYRAN-2-YL)ETHYL)-3,7-DIMETHYL-1,2,3,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL 2-METHYLBUTANOATE ; 8-[2-(4-HYDROXY-6-OXOTETRAHYDRO-2H-PYRAN-2-YL)ETHY L]-3,7-DIMETHYL-1,2,3,7,8,8A-HEXAHYDRO-1-NAPHTHALE ; 6-A-METHYLCOMPACTIN ; MEVINOLIN ; MEVINACOR ; 6-ALPHA-METHYLCOMPACTIN ; 2BETA,6ALPHA-DIMETHYL-8ALPHA-(2-METHYL-1-OXOBUTOXY)-MEVINIC ACID LACTONE ; (1S,3R,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-3,7-DIMETHYL-8-(2-(2R,4R)-(TETRAHYDRO-4-HYDROXY-6-OXO-2H-PYRAN-2-YL)ETHYL)-1-NAPHTHALENYL (S)-2-METHYL-BUTYRATE ; LOVASTATION ; LOVASTIN ; MONACOLIN K |
| pro_mdlNumber： | MFCD00072164 |
| pro_acceptors： | 5 |
| pro_donors： | 1 |
| pro_smile： | CC[C@H](C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C |
| InChi： | InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1 |
| InChiKey： | InChIKey=PCZOHLXUXFIOCF-BXMDZJJMSA-N |
property |
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| MeltingPoint： | 175 oC |
| Comments： | FOR PEAK IDENTIFICATION GENERAL DESCRIPTION: THIS PRODUCT IS PROVIDED AS DELIVERED AND SPECIFIED BY THE ISSUING PHARMACOPOEIA. ALL INFORMATION PROVIDED IN SUPPORT OF THIS PRODUCT, INCLUDING MSDS AND ANY PRODUCT INFORMATION LEAFLETS HAVE BEEN DEVELOPED AND ISSUED UNDER THE AUTHORITY OF THE ISSUING PHARMACOPOEIA. FOR FURTHER INFORMATION AND SUPPORT PLEASE GO TO THE WEBSITE OF THE ISSUING PHARMACOPOEIA OTHER NOTES: SALES RESTRICTIONS MAY APPLY |
secure_info |
|
| secure_symbol： |
GHS07
|
| secure_signal_word： | Warning |
| secure_risk_stmt： | H302 |
| secure_security_stmt： | S:S22;S24/25; |
| secure_wgk_germany： | 3 |
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