basic_info |
|
| Product_Name： | 氯霉素 |
| CAS： | 56-75-7 |
| 中文同义词： | 氯霉素 |
| EnglishSynonyms： | D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-4-NITROPHENETHYL]ACETAMIDE ; FENICOL ; CHLOROPTIC ; 2,2-DICHLORO-N-[2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL]ACETAMIDE ; D-(-)-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-BETA-(4-NITROPHENYL)ETHYL]ACETAMIDE ; PANTOVERNIL ; CHLOROMYCETIN ; CHLORAMPHENICOL 99% ; 2,2-DICHLORO-N-(1,3-DIHYDROXY-1-(4-NITROPHENYL)PROPAN-2-YL)ACETAMIDE ; AQUAMYCETIN ; D-THREO-N-DICHLOROACETYL-1-P-NITROPHENYL-2-AMINO-1,3-PROPANEDIOL ; CHLORAMPHENICOL LEVO ; D-THREO-2-DICHLOROACETAMIDO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL ; D-2-DICHLOROACETAMIDO-1-P-NITRO-PHENYL-1,3-PROPANEDIOL ; ALFICETYN ; SYNQUEST 4656-5-Y2 ; PARAXIN ; CHLOROMYCETIN(R) ; D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA(HYDROXYMETHYL)-BETA-(4-NITROPHENYL)ETHYL]ACETAMIDE ; MYCHEL ; VETICOL ; D-(-)-THREO-2-DICHLOROACETAMIDO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL ; ANACETIN ; CHLORAMPHENICOL 98-100.5% USP BP ; CHLORNITROMYCIN ; CHLORAMPHENICOL ; ACETAMIDE, 2,2-DICHLORO-N-[(1R,2R)-2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL]- ; D-THREO-1-(P-NITROPHENYL)-2-(DICHLOROACETYLAMINO)-1,3-PROPANEDIOL ; 2,2-DICHLORO-N-[(1R,2R)-1,3-DIHYDROXY-1-(4-NITROPHENYL)PROPAN-2-YL]ACETAMIDE ; EMBACETIN ; 2,2-DICHLORO-N-[(1R,2R)-2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL]ACETAMIDE ; CHLOROCID ; CHLOMIN ; D-(-)-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXY-METHYL)-P-NITROPHENYLETHYL]ACETAMIDE ; CHLORAMPHENICOLUM |
| pro_mdlNumber： | MFCD00078159 |
| pro_acceptors： | 7 |
| pro_donors： | 3 |
| pro_smile： | c1cc(ccc1[C@H]([C@@H](CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] |
| InChi： | InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1 |
| InChiKey： | InChIKey=WIIZWVCIJKGZOK-RKDXNWHRSA-N |
property |
|
| MeltingPoint： | 148-150 DEG C(LIT)/149-153℃/149-153℃ |
| Boiling_Point： | 645°C |
| Density： | 1.49 g/cm3 |
| Comments： | BIOCHEM/PHYSIOL ACTIONS: MODE OF ACTION: INHIBITS TRANSLATION ON THE 50S RIBOSOMAL SUBUNIT AT THE PEPTIDYLTRANSFERASE STEP (ELONGATION INHIBITION). BACTERIOSTATIC.MODE OF RESISTANCE: ACETYLATION BY CHLORAMPHENICOL ACETYLTRANSFERASE (CAT GENE) GENERAL DESCRIPTION: THIS PRODUCT IS PROVIDED AS DELIVERED AND SPECIFIED BY THE ISSUING PHARMACOPOEIA. ALL INFORMATION PROVIDED IN SUPPORT OF THIS PRODUCT, INCLUDING MSDS AND ANY PRODUCT INFORMATION LEAFLETS HAVE BEEN DEVELOPED AND ISSUED UNDER THE AUTHORITY OF THE ISSUING PHARMACOPOEIA. FOR FURTHER INFORMATION AND SUPPORT PLEASE GO TO THE WEBSITE OF THE ISSUING PHARMACOPOEIA OTHER NOTES: SALES RESTRICTIONS MAY APPLY |
secure_info |
|
| secure_symbol： |
GHS08
|
| secure_signal_word： | Danger |
| secure_risk_stmt： | H350 |
| secure_cautionary_stmt： | P201-P308 + P313 |
| secure_damage_code： | T |
| secure_risk_disclosure_stmt： | R:45 |
| secure_security_stmt： | S:53-45 |
| secure_wgk_germany： | 3 |
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