basic_info |
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| Product_Name： | (4-脒苯基)甲磺酰氟盐酸盐 |
| CAS： | 74938-88-8 |
| 中文同义词： | 对脒苯基甲磺酰氯盐酸盐 ; (4-脒苯基)甲磺酰氟盐酸盐 |
| EnglishSynonyms： | (4-CARBAMIMIDOYLPHENYL)METHANESULFONYL FLUORIDE HYDROCHLORIDE ; (P-AMIDINOPHENYL)METHANESULFONYL FLUORIDE HYDROCHLORIDE ; P-AMIDINOPHENYLMETHYL-SULFONYLFLUORIDE HYDROCHLORIDE ; 4-AMIDINOPHENYLMETHANESULFONYL FLUORIDE HYDROCHLORIDE ; P-AMIDINOPHENYLMETHYLSULFONYLFLUORIDE, HCL ; 4-AMIDINOBENZYLSULFONYL FLUORIDE HYDROCHLORIDE ; APMSF HCL ; 4-AMIDINOPHENYLMETHANESULPHONYL FLUORIDE HYDROCHLORIDE ; P-APMSF ; APMSF HYDROCHLORIDE ; 4-AMIDINOPHENYLMETHANESULFONYL-FLUORIDE-HCL ; P-APMSF HYDROCHLORIDE |
| pro_mdlNumber： | MFCD00078902 |
| pro_acceptors： | 4 |
| pro_donors： | 2 |
| pro_smile： | c1cc(ccc1CS(=O)(=O)F)C(=N)N.Cl |
| InChi： | InChI=1S/C8H9FN2O2S.ClH/c9-14(12,13)5-6-1-3-7(4-2-6)8(10)11;/h1-4H,5H2,(H3,10,11);1H |
| InChiKey： | InChIKey=KHLLRHIUKOJXLL-UHFFFAOYSA-N |
property |
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| MeltingPoint： | APPROX 205 DEG C (DEC) |
| Comments： | APPLICATION: APMSF WAS USED TO STUDY THE GLUCAGON-RECEPTOR INTERACTION APPLICATION: INHIBITION OF CAMP FORMATION LED TO THE CONCLUSION THAT THERE WAS A PREVIOUSLY UNEXPECTED SERINE RESIDUE IN THE ACTIVE SITE WHICH MAY OPERATE ON THE RECEPTOR BY A MECHANISM SIMILAR TO SERINE PROTEASES ASSAY METHOD: AT BIOCHEM/PHYSIOL ACTIONS: IRREVERSIBLE INHIBITOR OF SERINE PROTEASES WITH LYSINE OR ARGININE SUBSTRATE SPECIFICITIES. EFFECTIVE CONCENTRATION 10-100 MICROMOLE. FREQUENTLY USED TO CHARACTERIZE NEWLY DISCOVERED PROTEASES OTHER NOTES: AN IRREVERSIBLE INHIBITOR OF SERINE PROTEASES STORAGE TEMPERATURE: -20 DEG C UNSPSC: 12352200 WGK: 3 |
secure_info |
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| secure_wgk_germany： | 3 |
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