basic_info |
|
| Product_Name： | 环己酰亚胺 |
| CAS： | 66-81-9 |
| 中文同义词： | 环己酰亚胺 |
| EnglishSynonyms： | NEOCYCLOHEXIMIDE ; ACTIDIONE ; ZYGOMYCIN-D ; CYCLOHEXIMIDE ; ACTI-AID(R) ; ACTIDONE ; CYCLOHEXIMIDE, STREPTOMYCES GRISEUS ; 3-[2-(3,5-DIMETHYL-2-OXOCYCLOHEXYL)-2-HYDROXYETHYL]GLUTARIMIDE ; 4-[(2R)-2-[(1S,3S,5S)-3,5-DIMETHYL-2-OXOCYCLOHEXYL]-2-HYDROXYETHYL]PIPERIDINE-2,6-DIONE ; NARAMYCIN A ; CHX ; ACTIDION ; 4-[2-(3,5-DIMETHYL-2-OXO-CYCLOHEXYL)-2-HYDROXYETHYL]-2,6-PIPERIDINEDIONE ; BETA-[2-(3,5-DIMETHYL-2-OXOCYCLOHEXYL)-2-HYDROXYETHYL]GLUTARIMIDE ; [1S-[1ALPHA(S*),3ALPHA,5BETA]]-4-[2-(3,5-DIMETHYL-2-OXOCYCLOHEXYL)-2-HYDROXYETHYL]-2,6-PIPERIDINEDIONE ; ACTI-AID ; NSC-185 ; NARAMYCIN |
| pro_mdlNumber： | MFCD00082346 |
| pro_acceptors： | 5 |
| pro_donors： | 2 |
| pro_smile： | C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C |
| InChi： | InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1 |
| InChiKey： | InChIKey=YPHMISFOHDHNIV-FSZOTQKASA-N |
property |
|
| Comments： | BIOCHEM/PHYSIOL ACTIONS: CYCLOHEXIMIDE (CHX) IS AN ANTIBIOTIC PRODUCED BY S. GRISEUS. ITS MAIN BIOLOGICAL ACTIVITY IS TRANSLATION INHIBITION IN EUKARYOTES RESULTING IN CELL GROWTH ARREST AND CELL DEATH. CHX IS WIDELY USED FOR SELECTION OF CHX-RESISTANT STRAINS OF YEAST AND FUNGI, CONTROLLED INHIBITION OF PROTEIN SYNTHESIS FOR DETECTION OF SHORT-LIVED PROTEINS AND SUPER-INDUCTION OF PROTEIN EXPRESSION, AND APOPTOSIS INDUCTION OR FACILITATION OF APOPTOSIS INDUCTION BY DEATH RECEPTORS RIDADR: UN 2811 6.1/PG 1 RTECS: MA4375000 WGK: 3 |
| Concentration： | 0.1% |
secure_info |
|
| secure_symbol： |
GHS06
GHS08
GHS09
|
| secure_signal_word： | Danger |
| secure_risk_stmt： | H300-H341-H360D-H411 |
| secure_cautionary_stmt： | P201-P264-P273-P281-P301 + P310-P308 + P313 |
| secure_damage_code： | Xn |
| secure_risk_disclosure_stmt： | R:22 |
| secure_security_stmt： | S:53-45-61 |
| secure_wgk_germany： | 3 |
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