基本信息 |
|
| 产品名称： | 环磷酰胺 |
| CAS： | 6055-19-2 |
| 中文同义词： | 环磷酰胺，一水 ; 环磷酰胺一水物 ; 2-[N,N-双(2-氯乙基)]-1,3,2-氧氮磷杂环己烷-2-氧化物一水合物 ; 环磷酰胺 |
| 英文同义词： | CYCLOPHOSPHAMIDE HYDRATE ; CYCLOPHOSPHAMID MONOHYDRATE ; CYCLOPHOSPHANE MONOHYDRATE ; N,N-BIS(BETA-CHLOROETHYL)-N',O-PROPYLENEPHOSPHORIC ACID ESTER AMIDE MONOHYDRATE ; CYCLOPHOSPHAMIDE MONOHYDRATE ; 2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE MONOHYDRATE ; 2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE ; ENDOXON ; BIS(2-CHLOROETHYL)PHOSPHORAMIDE CYCLIC PROPANOLAMIDE ESTER ; 2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-1,3,2-OXAZAPHOSPHORIN-2-OXIDE MONOHYDRATE ; N,N-BIS(2-CHLOROETHYL)TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORIN-2-AMINE-2-OXIDE MONOHYDRATE ; CPA ; CYTOXAN ; BIS(2-CHLOROETHYL)PHOSPHORAMIDE CYCLIC PROPANOLAMIDE ESTER MONOHYDRATE ; CYCLOPHOSPHAMIDE MONOHYDRATE 98+% ; CYTOXAN MONOHYDRATE ; ENDOXAN A MONOHYDRATE ; CYCLOPHOSPHANE ; 2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE HYDRATE ; 2-[BIS(2-CHLOROETHYL)AMINO]-1,3,2LAMBDA(5)-OXAZAPHOSPHINAN-2-ONE HYDRATE ; CYCLOPHOSPHAMIDE |
| MDL号： | MFCD00149395 |
| 氢键受体数量： | 4 |
| 氢键供体数量： | 1 |
| Smile： | C1CNP(=O)(OC1)N(CCCl)CCCl.O |
| InChi： | InChI=1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2 |
| InChiKey： | InChIKey=PWOQRKCAHTVFLB-UHFFFAOYSA-N |
性质 |
|
| 熔点： | 49-51 DEG C(LIT) |
| 沸点： | >110 DEG C |
| 物理性质： | FLASHPOINT: 113 DEG C FLASHPOINT: 235.4 DEG F |
| 注解： | BIOCHEM/PHYSIOL ACTIONS: CYCLOPHOSPHAMIDE IS A CYTOTOXIC NITROGEN MUSTARD DERIVATIVE WIDELY USED IN CANCER CHEMOTHERAPY. IT CROSS-LINKS DNA, CAUSES STRAND BREAKAGE, AND INDUCES MUTATIONS. ITS CLINICAL ACTIVITY IS ASSOCIATED WITH A DECREASE IN ALDEHYDE DEHYDROGENASE 1 (ALDH1) ACTIVITY RIDADR: UN 3464 6.1/PG 3 RTECS: RP6157750 SOLUBILITY: H2O: SOLUBLE 0.1 G/ML, CLEAR, COLORLESS STORAGE TEMPERATURE: 2-8 DEG C UNSPSC: 12352200 WGK: 3 |
安全信息 |
|
| 符号： |
GHS06
GHS08
|
| 信号词： | Danger |
| 危险声明： | H301-H350 |
| 警示性声明： | P201-P301 + P310-P308 + P313 |
| 危害码： | T |
| 风险声明： | R:45-25 |
| 安全声明： | S:53-45 |
| WGK德国： | 3 |
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