硫酸庆大霉素 ,1403-66-3

硫酸庆大霉素

CAS号: 1403-66-3 ;1405-41-0
CCD编号: CCD00115628
分子式: C21 H43 N5 O7 . C20 H41 N5 O7 . C19 H39 N5 O7 . H2 O4 S
分子量: 1488.79

基本信息
产品名称：	硫酸庆大霉素
CAS：	1403-66-3 ;1405-41-0
中文同义词：	硫酸庆大霉素
英文同义词：	GENTIOMYCIN C SULFATE SALT ; GENTAMICIN SULPHATE ; GENTAMYCINUM ; GENOPTIC SULFATE ; GENTAMYCIN SULPHATE ; GENTAMICIN C(SUB 1A) ; GENTAMICIN SULFATE CELL CULTURE TESTED ; O-3-DEOXY-4-C-METHYL-3-(METHYLAMINO)-BETA-L-ARABINOPYRANOSYL-(1-6)-O-(2,6-DIAMINO-2,3,4,6-TETRADEOXY-ALPHA-D-ERYTHRO-HEXOPYRANOSYL-(1-4))-2-DEOXY-D-STREPTAMINE ; GENTAMICIN SULFATE USP GRADE 99% ; (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDROXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)TETRAHYDRO-2H-PYRAN-3,5-DIOL SULFATE ; GENTAMICIN ; GENTAMICIN SULFATE ; GENTACYCOL ; GENOPTIC ; GARAMYCIN ; GARAMYCIN SULFATE ; GENTAMICIN SULFATE SALT ; GENTAMYCIN SULFATE ; GENTAMICINS ; GARAMYCIN SULFATE SALT ; GENTIOMYCIN C ; GM SULFATE ; GENTAMICIN C COMPLEX SULFATE
MDL号：	MFCD00270181
氢键受体数量：	12
氢键供体数量：	8
Smile：	C[C@H]([C@@H]1CC[C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@](CO3)(C)O)NC)O)N)N)N)N.C[C@H]([C@@H]1CC[C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@](CO3)(C)O)NC)O)N)N)N)NC.C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H](CC[C@H](O3)CN)N)N)N)O.OS(=O)(=O)O
InChi：	InChI=1S/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19;1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;8-19,25-28H,4-7,21-24H2,1-3H3;8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+;8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+;8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m110./s1
InChiKey：	InChIKey=RDEIXVOBVLKYNT-HDZPSJEVSA-N
性质
注解：	BIOCHEM/PHYSIOL ACTIONS: MODE OF ACTION: GENTAMICIN CAUSES CODON MISREADING BY BINDING TO THE 30S RIBOSOMAL SUBUNIT, BLOCKING THE TRANSLOCATION OF PEPTIDYL-TRNA FROM THE ACCEPTOR SITE TO THE DONOR SITE. THE BACTERICIDAL EFFECT OF GENTAMICIN ON PSEUDOMONAS AERUGINOSA IS EXERTED BY THE BINDING OF GENTAMICIN TO THE OUTER MEMBRANE, WHERE IT DISPLACES NATURAL CATIONS, DESTABILIZES THE MEMBRANE, AND FORMS HOLES IN THE CELL SURFACE. ANTIMICROBIAL SPECTRUM: GRAM-NEGATIVE BACTERIA, STAPHYLOCOCCUS AUREUS AND OTHER GRAM-POSITIVE BACTERIA GENERAL DESCRIPTION: THIS PRODUCT IS PROVIDED AS DELIVERED AND SPECIFIED BY THE ISSUING PHARMACOPOEIA. ALL INFORMATION PROVIDED IN SUPPORT OF THIS PRODUCT, INCLUDING MSDS AND ANY PRODUCT INFORMATION LEAFLETS HAVE BEEN DEVELOPED AND ISSUED UNDER THE AUTHORITY OF THE ISSUING PHARMACOPOEIA. FOR FURTHER INFORMATION AND SUPPORT PLEASE GO TO THE WEBSITE OF THE ISSUING PHARMACOPOEIA OTHER NOTES: SALES RESTRICTIONS MAY APPLY
浓度：	50mg/mLgentamicin
安全信息
符号：	GHS08
信号词：	Danger
危险声明：	H317-H334
警示性声明：	P261-P280-P342 + P311
危害码：	Xn
风险声明：	R:42/43
安全声明：	S:23-36/37-45
WGK德国：	nwg

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硫酸庆大霉素

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