basic_info |
|
| Product_Name： | 硫酸庆大霉素 |
| CAS： | 1403-66-3 ;1405-41-0 |
| 中文同义词： | 硫酸庆大霉素 |
| EnglishSynonyms： | GARAMYCIN SULFATE ; GENTAMICIN C(SUB 1A) ; GENTAMICIN ; GENTAMICIN SULFATE ; GENTAMICIN SULFATE SALT ; GENTAMICIN SULPHATE ; GENTAMICINS ; GENOPTIC SULFATE ; GENTAMICIN SULFATE USP GRADE 99% ; GM SULFATE ; GENTIOMYCIN C SULFATE SALT ; GENTAMICIN C COMPLEX SULFATE ; O-3-DEOXY-4-C-METHYL-3-(METHYLAMINO)-BETA-L-ARABINOPYRANOSYL-(1-6)-O-(2,6-DIAMINO-2,3,4,6-TETRADEOXY-ALPHA-D-ERYTHRO-HEXOPYRANOSYL-(1-4))-2-DEOXY-D-STREPTAMINE ; GENTACYCOL ; GENOPTIC ; GARAMYCIN ; GENTAMICIN SULFATE CELL CULTURE TESTED ; (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDROXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)TETRAHYDRO-2H-PYRAN-3,5-DIOL SULFATE ; GARAMYCIN SULFATE SALT ; GENTAMYCINUM ; GENTIOMYCIN C ; GENTAMYCIN SULFATE ; GENTAMYCIN SULPHATE |
| pro_mdlNumber： | MFCD00270181 |
| pro_acceptors： | 12 |
| pro_donors： | 8 |
| pro_smile： | C[C@H]([C@@H]1CC[C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@](CO3)(C)O)NC)O)N)N)N)N.C[C@H]([C@@H]1CC[C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@](CO3)(C)O)NC)O)N)N)N)NC.C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H](CC[C@H](O3)CN)N)N)N)O.OS(=O)(=O)O |
| InChi： | InChI=1S/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19;1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;8-19,25-28H,4-7,21-24H2,1-3H3;8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+;8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+;8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m110./s1 |
| InChiKey： | InChIKey=RDEIXVOBVLKYNT-HDZPSJEVSA-N |
property |
|
| Comments： | BIOCHEM/PHYSIOL ACTIONS: MODE OF ACTION: GENTAMICIN CAUSES CODON MISREADING BY BINDING TO THE 30S RIBOSOMAL SUBUNIT, BLOCKING THE TRANSLOCATION OF PEPTIDYL-TRNA FROM THE ACCEPTOR SITE TO THE DONOR SITE. THE BACTERICIDAL EFFECT OF GENTAMICIN ON PSEUDOMONAS AERUGINOSA IS EXERTED BY THE BINDING OF GENTAMICIN TO THE OUTER MEMBRANE, WHERE IT DISPLACES NATURAL CATIONS, DESTABILIZES THE MEMBRANE, AND FORMS HOLES IN THE CELL SURFACE. ANTIMICROBIAL SPECTRUM: GRAM-NEGATIVE BACTERIA, STAPHYLOCOCCUS AUREUS AND OTHER GRAM-POSITIVE BACTERIA GENERAL DESCRIPTION: THIS PRODUCT IS PROVIDED AS DELIVERED AND SPECIFIED BY THE ISSUING PHARMACOPOEIA. ALL INFORMATION PROVIDED IN SUPPORT OF THIS PRODUCT, INCLUDING MSDS AND ANY PRODUCT INFORMATION LEAFLETS HAVE BEEN DEVELOPED AND ISSUED UNDER THE AUTHORITY OF THE ISSUING PHARMACOPOEIA. FOR FURTHER INFORMATION AND SUPPORT PLEASE GO TO THE WEBSITE OF THE ISSUING PHARMACOPOEIA OTHER NOTES: SALES RESTRICTIONS MAY APPLY |
| Concentration： | 50mg/mLgentamicin |
secure_info |
|
| secure_symbol： |
GHS08
|
| secure_signal_word： | Danger |
| secure_risk_stmt： | H317-H334 |
| secure_cautionary_stmt： | P261-P280-P342 + P311 |
| secure_damage_code： | Xn |
| secure_risk_disclosure_stmt： | R:42/43 |
| secure_security_stmt： | S:23-36/37-45 |
| secure_wgk_germany： | nwg |
* If the product has intellectual property rights, a license granted is must or contact us.
2010-2025 © Chemical Cloud Database. ALL Rights Reserved.浙ICP备11020424号-1
浙公网安备 33010802004002号
English