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| Product_Name： | 克拉霉素 |
| CAS： | 81103-11-9 |
| 中文同义词： | 克拉霉素 ; 克拉仙 ; 克拉红霉素 |
| EnglishSynonyms： | FROMILID ; KLARICID ; CLARITHROMYCIN ; CLAREM ; 6-(4-DIMETHYLAMINO-3-HYDROXY-6-METHYLTETRAHYDROPYRAN-2-YL-OXY)-14-ETHYL-12,13-DIHYDROXY-4-(5-HYDROXY ; CRIXAN ; INFEX ; CLACEE ; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL)OXY)-14-ETHYL-12,13-DIHYDROXY-4-(((2R,4R,5S,6S)-5-HYDROXY-4-METHOXY-4,6-DIMETHYLTETRAHYDRO-2H-PYRAN-2-YL)OXY)-7-METHOXY-3,5,7,9,11,13-HEXAMETHYLOXACYCLOTETRADECANE-2,10-DIONE ; CLARI ; CLACID ; CLARITHROMYCINE ; BIAXIN ; VIKROL ; CLARIPEN ; KLABAX ; KLACID ; 6-O-METHYLERYTHROMYCIN ; CLARIDAR |
| pro_mdlNumber： | MFCD00865140 |
| pro_acceptors： | 14 |
| pro_donors： | 4 |
| pro_smile： | CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)O)(C)O |
| InChi： | InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 |
| InChiKey： | InChIKey=AGOYDEPGAOXOCK-KCBOHYOISA-N |
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| Comments： | BIOCHEM/PHYSIOL ACTIONS: CLARITHROMYCIN IS A MACROLIDE ANTIBIOTIC. IT PREVENTS BACTERIAL GROWTH BY INTERFERING WITH PROTEIN SYNTHESIS. CLARITHROMYCIN IS AN ACID-STABLE VERSION OF ERYTHROMYCIN AND IS PARTICULARLY EFFECTIVE AGAINST GRAM-NEGATIVE BACTERIA. IT HAS A SHORT HALF-LIFE, HOWEVER ITS METABOLITE, 14-HYDROXY CLARITHROMYCIN IS NEARLY TWICE AS ACTIVE AS CLARITHROMYCIN AGAINST CERTAIN BACTERIA GENERAL DESCRIPTION: THIS PRODUCT IS PROVIDED AS DELIVERED AND SPECIFIED BY THE ISSUING PHARMACOPOEIA. ALL INFORMATION PROVIDED IN SUPPORT OF THIS PRODUCT, INCLUDING MSDS AND ANY PRODUCT INFORMATION LEAFLETS HAVE BEEN DEVELOPED AND ISSUED UNDER THE AUTHORITY OF THE ISSUING PHARMACOPOEIA. FOR FURTHER INFORMATION AND SUPPORT PLEASE GO TO THE WEBSITE OF THE ISSUING PHARMACOPOEIA OTHER NOTES: SALES RESTRICTIONS MAY APPLY |
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