basic_info |
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| Product_Name： | ANGIOSTATIN, HUMAN |
| CAS： | 86090-08-6 |
| EnglishSynonyms： | ANGIOSTATIN, HUMAN, BIOACTIVE ; ANGIOSTATIN(R) PROTEIN, HUMAN ; ANGIOSTATIN, HUMAN ; ANGIOSTATIN |
| pro_mdlNumber： | MFCD01864016 |
| pro_acceptors： | 0 |
| pro_donors： | 0 |
| InChi： | InChI=1S// |
| InChiKey： | InChIKey=MOSFIJXAXDLOML-UHFFFAOYSA-N |
property |
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| Comments： | APPLICATIONS: ANGIOGENESIS INHIBITOR ASSAY BY SDS PAGE DESCRIPTION: ANGIOSTATIN IS AN ANGIOGENESIS INHIBITOR THAT SELECTIVELY INSTRUCTS ENDOTHELIUM TO BECOME REFRACTORY TO ANGIOGENIC STIMULI DESCRIPTION: ANGIOSTATIN IS NOT YET AVAILABLE FOR CLINICAL STUDIES, BUT EXPERIMENTS WITH ANGIOSTATIN HAVE PROVIDED PROOF OF PRINCIPAL THAT INHIBITION OF ANGIOGENESIS MAY PROLONG TUMOR DORMANCY DESCRIPTION: ANGIOSTATIN, WHICH SPECIFICALLY INHIBITS ENDOTHELIAL PROLIFERATION INDUCED DORMANCY OF METASTASIS DEFINED BY A BALANCE OF APOPTOSIS END PROLIFERATION DESCRIPTION: IT HAS BEEN OBSERVED THAT SYSTEMATIC ADMISTRATION OF HUMAN ANGIOSTATIN LEADS TO ALMOST COMPLETE INHIBITION OF TUMOR GROWTH WITHOUT DETECTABLE TOXICITY OR RESISTANCE DESCRIPTION: SERUM PROTEIN, ANGIOGENESIS REAGENT PURIFIED FROM HUMAN PLASMINOGEN DESCRIPTION: THE MECHANISM OF ACTION OF ANGIOSTATIN IS PRESENTLY UNCLEAR FORM: IN PBS, PH 7.2 MATERIAL SAFETY: ALL PRODUCTS ARE FOR RESEARCH OR MANUFACTURING PURPOSES ONLY, AND ARE NOT FOR USE IN HUMAN THERAPEUTIC PROCEDURES MATERIAL SAFETY: PROPER LABORATORY PROCEDURES SHOULD BE USED IN HANDLING ORIGINAL CATALOG NUMBER: HANG-1-100 RELATED DISCIPLINES: APOPTOSIS, ANALYTICAL CYTOLOGY SHIPPING CONDITIONS: BLUE ICE STORAGE CONDITIONS: +4 DEG C |
| Information： | SOURCE ORGANISM: HUMAN PLASMA |
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