basic_info |
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| Product_Name： | IMMOBILIZED NEUTRAVIDIN(TM) ON AGAROSE |
| EnglishSynonyms： | IMMOBILIZED NEUTRAVIDIN(TM) ON AGAROSE |
| pro_mdlNumber： | MFCD03099671 |
| pro_acceptors： | 0 |
| pro_donors： | 0 |
| InChi： | InChI=1S// |
| InChiKey： | InChIKey=MOSFIJXAXDLOML-UHFFFAOYSA-N |
property |
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| Comments： | APPLICATIONS: IMMUNOPRECIPITATION APPLICATIONS: PURIFYING PROTEINS THAT BIND TO BIOTINYLATED LIGANDS COMMENT 1: WHEN NONSPECIFIC BINDING IS A PROBLEM IN YOUR APPLICATION, PIERCE OFFERS A VARIETY OF IMMOBILIZED NEUTRAVIDIN(TM) PRODUCTS AS SUPERIOR ALTERNATIVES TO AVIDIN OR STREPTAVIDIN COMMENT 2: NEUTRAVIDIN(TM) BIOTIN-BINDING PROTEIN IS A MODIFIED AVIDIN DERIVATIVE THAT COMBINES SEVERAL KEY FEATURES TO PROVIDE A BIOTIN-BINDING WITH EXCEPTIONALLY LOW NONSPECIFIC BINDING PROPERTIES COMMENT 3: NEUTRAVIDIN(TM) DOES NOT CONTAIN CARBOHYDRATE AND HAS AN IDEAL ISOELECTRIC POINT (6.3) FOR THE BEST UTILITY IN A VARIETY OF APPLICATIONS ECONOMICALLY PRICED IN JUMBO QUANTITIES FEATURES/BENEFITS: CARBOHYDRATE FREE: JUST LIKE STREPTAVIDIN, NEUTRAVIDIN(TM) BIOTIN-BINDING PROTEIN HAS NO CARBOHYDRATE, ELIMINATING NONSPECIFIC BINDING PROBLEMS DUE TO SUGARS FEATURES/BENEFITS: NEUTRAL PL: THIS ELIMINATES ELECTROSTATIC INTERACTION THAT CONTRIBUTES TO NONSPECIFIC BINDING FEATURES/BENEFITS: NEUTRAL PL: WITH A PL OF 6.3, NEUTRAVIDIN(TM) BIOTIN-BINDING PROTEIN HAS A PL THAT IS CLOSER TO NEUTRALITY THAN AVIDIN OR STREPTAVIDIN FEATURES/BENEFITS: NO INTERACTION WITH CELL SURFACE MOLECULES: ABSENCE OF THE ARG-TYR-ASP SEQUENCE (PRESENT IN STREPTAVIDIN), WHICH MIMICS THE UNIVERSAL CELL SURFACE RECOGNITION SEQUENCE PRESENT IN A VARIETY OF MOLECULES, ELIMINATES CROSS-REACTIVITY OF CELL SURFACE MOLECULES LESS NONSPECIFIC BINDING PRODUCES BETTER RESULTS AND BETTER YIELDS |
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