基本信息 |
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| 产品名称： | 阿达帕林 |
| CAS： | 106685-40-9 |
| 中文同义词： | 阿达帕林 |
| 英文同义词： | 6-(3-(ADAMANTAN-1-YL)-4-METHOXYPHENYL)-2-NAPHTHOIC ACID ; 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHALENE CARBOXYLIC ACID ; 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID ; CD-271 ; DIFFERIN ; ADAPALENE ; 2-NAPHTHALENECARBOXYLIC ACID, 6-(4-METHOXY-3-TRICYCLO[3.3.1.13,7]DEC-1-YLPHENYL)- ; 6-(4-METHOXY-3-TRICYCLO[3.3.1.13,7]DEC-1-YLPHENYL)-2-NAPHTHALENECARBOXYLIC ACID ; 6-(3-ADAMANTAN-1-YL-4-METHOXY-PHENYL)-NAPHTHALENE-2-CARBOXYLIC ACID ; 6-[3-(1-ADAMANTYL)-4-METHOXY-PHENYL]NAPHTHALENE-2-CARBOXYLIC ACID |
| MDL号： | MFCD03106112 |
| 氢键受体数量： | 3 |
| 氢键供体数量： | 1 |
| Smile： | COc1ccc(cc1[C@@]23C[C@H]4C[C@@H](C2)C[C@H](C4)C3)c5ccc6cc(ccc6c5)C(=O)O |
| InChi： | InChI=1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30)/t17-,18+,19-,28- |
| InChiKey： | InChIKey=LZCDAPDGXCYOEH-AADAIPAGSA-N |
性质 |
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| 注解： | BIOCHEM/PHYSIOL ACTIONS: RETINOIC ACID ANALOGUE THAT IS A RARBETA AND RARGAMMA AGONIST (AC50 VALUES ARE 2.2, 9.3, 22 AND > 1000 NM FOR RARBETA, RARGAMMA, RARALPHA AND RXRALPHA RECEPTORS RESPECTIVELY). INHIBITS PROLIFERATION AND INDUCES APOPTOSIS IN COLORECTAL CANCER CELLS IN VITRO. DISPLAYS COMEDOLYTIC ACTIVITY. ITS UNIQUE PHARMACOLOGICAL PROPERTIES MAKE IT SUPERIOR TO OTHER RETINOIDS FOR THE TREATMENT OF ACNE GENERAL DESCRIPTION: THIS PRODUCT IS PROVIDED AS DELIVERED AND SPECIFIED BY THE ISSUING PHARMACOPOEIA. ALL INFORMATION PROVIDED IN SUPPORT OF THIS PRODUCT, INCLUDING MSDS AND ANY PRODUCT INFORMATION LEAFLETS HAVE BEEN DEVELOPED AND ISSUED UNDER THE AUTHORITY OF THE ISSUING PHARMACOPOEIA. FOR FURTHER INFORMATION AND SUPPORT PLEASE GO TO THE WEBSITE OF THE ISSUING PHARMACOPOEIA OTHER NOTES: SALES RESTRICTIONS MAY APPLY |
安全信息 |
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| WGK德国： | nwg |
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