BAZ2-ICR_ChemCD

BAZ2-ICR

basic_info
Product_Name：	BAZ2-ICR
EnglishSynonyms：	4-[4-(1-METHYL-1H-PYRAZOLE-4-YL)-1-[2-(1-METHYL-1H-PYRAZOL-4-YL)ETHYL]-1H-IMIDAZOL-5-YL]BENZONITRILE ; BAZ2-ICR ; BAZ2ICR
pro_acceptors：	0
pro_donors：	0
pro_smile：	CN1N=CC(=C1)C=1N=CN(C1C1=CC=C(C#N)C=C1)CCC=1C=NN(C1)C
InChi：	InChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24-26(2)13-18)20(27)17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3
InChiKey：	InChIKey=RRZVGDGTWNQAPW-UHFFFAOYSA-N
property
Comments：	Selective BAZ2 bromodomain inhibitor (Kd values are 109 and 170 nM for BAZ2A and BAZ2B respectively). Exhibits 15-fold selectivity for the BAZ2 bromodomain over the CERC2 bromodomain and >100-fold selectivity over a range of other bromodomains. Accelerates FRAP recovery in a BAZ2A FRAP assay.For the detailed information of BAZ2-ICR, the solubility of BAZ2-ICR in water, the solubility of BAZ2-ICR in DMSO, the solubility of BAZ2-ICR in PBS buffer, the animal experiment (test) of BAZ2-ICR, the cell expriment (test) of BAZ2-ICR, the in vivo, in vitro and clinical trial test of BAZ2-ICR, the EC50, IC50,and affinity,of BAZ2-ICR
secure_info

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