基本信息 |
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| 产品名称： | BV6 |
| CAS： | 1001600-56-1 |
| 英文同义词： | BV-6 ; (2S)-2-{[(2S)-1-[(2S)-2-CYCLOHEXYL-2-[(2S)-2- (METHYLAMINO)PROPANAMIDO]ACETYL]PYRROLIDIN-2- YL]FORMAMIDO}-N-{6-[(2S)-2-{[(2S)-1-[(2S)-2- CYCLOHEXYL-2-[(2S)-2- (METHYLAMINO)PROPANAMIDO]ACETYL]PYRROLIDIN-2- YL]FORMAMIDO}-3,3-DIPHENYLPROPANAMIDO]HEXYL}-3,3- DIPHENYLPROPANAMIDE ; BV6 |
| 氢键受体数量： | 0 |
| 氢键供体数量： | 0 |
| Smile： | C1(CCCCC1)[C@@H](C(=O)N1[C@@H](CCC1)C(=O)N[C@H](C(=O)NCCCCCCNC([C@H](C(C1=CC=CC=C1)C1=CC=CC=C1)NC(=O)[C@H]1N(CCC1)C([C@@H](NC([C@H](C)NC)=O)C1CCCCC1)=O)=O)C(C1=CC=CC=C1)C1=CC=CC=C1)NC([C@H](C)NC)=O |
| InChi： | InChI=1S/C70H96N10O8/c1-47(71-3)63(81)75-59(53-37-21-11-22-38-53)69(87)79-45-27-41-55(79)65(83)77-61(57(49-29-13-7-14-30-49)50-31-15-8-16-32-50)67(85)73-43-25-5-6-26-44-74-68(86)62(58(51-33-17-9-18-34-51)52-35-19-10-20-36-52)78-66(84)56-42-28-46-80(56)70(88)60(54-39-23-12-24-40-54)76-64(82)48(2)72-4/h7-10,13-20,29-36,47-48,53-62,71-72H,5-6,11-12,21-28,37-46H2,1-4H3,(H,73,85)(H,74,86)(H,75,81)(H,76,82)(H,77,83)(H,78,84)/t47-,48-,55-,56-,59-,60-,61-,62-/m0/s1 |
| InChiKey： | InChIKey=DPXJXGNXKOVBJV-YLOPQIBLSA-N |
性质 |
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| 注解： | BV6 induced apoptotic and necrotic cell death in monocytes while T-cells, dendritic cells and macrophages were largely protected against BV6-induced cell death. In immature dendritic cells BV6 treatment resulted in moderate activation of the classical NFkB pathway, but it also diminished the stronger NFkB-inducing effect of TNF and CD40L. Despite its inhibitory effect on TNF- and CD40L signaling, BV6 was able to trigger maturation of immature DCs as indicated by upregulation of CD83, CD86 and IL12.For the detailed information of BV6, the solubility of BV6 in water, the solubility of BV6 in DMSO, the solubility of BV6 in PBS buffer, the animal experiment (test) of BV6, the cell expriment (test) of BV6, the in vivo, in vitro and clinical trial test of BV6, the EC50, IC50,and Affinity of BV6 |
| 规格： | BV6 induced apoptotic and necrotic cell death in monocytes while T-cells, dendritic cells and macrophages were largely protected against BV6-induced cell death. |
安全信息 |
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