EPZ015666 ,1616391-65-1 _化学云数据库

EPZ015666

基本信息
产品名称：	EPZ015666
CAS：	1616391-65-1
英文同义词：	EPZ-015666,EPZ 015666 ; (S)-N-(3-(3,4-DIHYDROISOQUINOLIN-2(1H)-YL)-2-HYDROXYPROPYL)-6-(OXETAN-3-YLAMINO)PYRIMIDINE-4-CARBOXAMIDE ; EPZ015666
氢键受体数量：	0
氢键供体数量：	0
Smile：	C1N(CCC2=CC=CC=C12)C[C@H](CNC(=O)C1=NC=NC(=C1)NC1COC1)O
InChi：	InChI=1S/C20H25N5O3/c26-17(10-25-6-5-14-3-1-2-4-15(14)9-25)8-21-20(27)18-7-19(23-13-22-18)24-16-11-28-12-16/h1-4,7,13,16-17,26H,5-6,8-12H2,(H,21,27)(H,22,23,24)/t17-/m0/s1
InChiKey：	InChIKey=ZKXZLIFRWWKZRY-KRWDZBQOSA-N
性质
信息：	EPZ015666 is a potent, selective and orally bioavailable PRMT5 inhibitor with Ki of 5 nM, >20,000-fold selectivity over other PMTs.
安全信息

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